Cutillas Lab

We use large-scale functional assays, proteomics and computational approaches to investigate the mechanisms that regulate intracellular signalling pathways driven by kinase activity. A particular research focus of the group involves dissecting the heterogeneity of regulatory mechanisms that drive diversity of signalling circuits across different tumour types.

We address the challenge that circuitry information is missing from standard omics data. Our hypothesis that this knowledge is key to fully understand signalling regulation and for the development of next generation tools for precision medicine.